Please use this searchable database to view abstract information from our 53rd Annual Symposium in 2024

Abstract Title

Laryngopharyngeal Reflux in Patients Who Declined Robotic or Laparoscopic Nissen Fundoplication: Voice Outcomes

Abstract

Objective: To evaluate whether Robotic or Laparoscopic Nissen Fundoplication (LNF) promotes improved voice outcomes and symptoms in patients with Laryngopharyngeal Reflux (LPR) compared to patients who were candidates for surgery but elected to receive treatment with anti-reflux medical management alone.

Methods: A retrospective chart review was conducted of patients who visited the office of the senior author, received a diagnosis of LPR, and were candidates for LNF. Patients were categorized into two groups: those who received LNF surgery (Nissen received, n=64) and those who declined surgery (Nissen declined, n=55). Reflux Finding Scores (RFS) collected pre- and post-treatment were compared between groups. RFS scoring was provided by a laryngology fellow and two otolaryngology residents who received at least four months of training with the senior author. 24-hour pH-impedance results also were evaluated pre- and post-treatment, respectively.

Results: 24-hour pH-impedance testing from patients in the Nissen received group showed a statistically significant decrease in three subcategories when monitoring occurred at the proximal esophagus compared to the Nissen declined group: 1) total reflux events proximal (mean difference pre-post-surgery=43.19 ± 62.94 vs. mean difference pre-post medication=7.07 ± 19.86, p=0.003), 2) upright events proximal (41.05 ± 52.60 vs. 4.45 ± 18.03, p=0.006), 3) weakly acidic events proximal (33.37 ± 45.07 vs. -4.64 ± 14.53, p<0.001). The Nissen received group showed improved total RFS scores compared to the Nissen declined group. However, these differences were not statistically significant; but the RFS subcategory score for diffuse laryngeal edema was statistically significant (0.37 ± 1.10 vs. -0.06 ± 0.82, p=0.034). Only one of three raters completed ratings; thus, these RFS results are preliminary.

Conclusion: LNF is more beneficial for controlling LPR in patients who qualify for surgery than treatment with medication alone.

First NameAdam
Last NameGardi
Author #2 First NameSriprachodaya
Author #2 Last NameGaddam
Author #3 First NamePhilip
Author #3 Last NameMaxwell
Author #4 First NameParastou
Author #4 Last NameRanjbar
Author #5 First NameOmar
Author #5 Last NameRamadan
Author #6 First NameRobert
Author #6 Last NameSataloff