| Abstract | Objective: To study the laryngeal functional characteristics of patients with motor neuron disease diagnosed at the voice clinic and provide reference for otolaryngologists to identify motor neuron disease in the early stage.
Method: A retrospective analysis was conducted on the laryngeal functional characteristics of 7 patients with motor neuron disease who visited the voice clinic ultimately diagnosed by neurologists, including data from stroboscope, fiberoptic endoscopic examination of swallowing（FEES）, and laryngeal electromyography(LEMG).
Result: There were 5 males and 2 females, with an average age of 60.85 ± 13.18 years. The main complaints of the patient at the time of treatment were discomfort in the pharynx, voice change, or vocal fatigue. They had previously visited the otolaryngology department more than twice, with one patient undergoing epiglottic cyst surgery in an external hospital. All patients showed mild swallowing dysfunction, 4 cases had secretions on the lateral pharyngeal wall, 3 cases had mild or moderate fluid accumulation in the pyriform fossa, and swallowing laryngoscopy showed mild or moderate food residue in the epiglottic valley and pyriform fossa, all without leakage or aspiration. Stroboscopic laryngoscopy showed that 6 patients had glottic insufficiency, 4 had supraglottic compression, 3 had silent supraglottic compression, 3 had normal vocal cord movement, and 4 had decreased vocal cord movement. The LEMG examination of 5 patients showed neurogenic lesions, while the LEMG examination of 2 patients was normal.
Conclusion: When there are abnormal manifestations of swallowing function and voice function, it is necessary to be vigilant about the possibility of motor neuron disease. LEMG examination is beneficial for early detection of motor neuron disease.
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