The Voice Foundation 2017 46th Annual Symposium: Care of the Professional Voice

Use of Adeno Associated Virus to Express Epithelial Transport Genes in the Vocal Folds

The Voice Foundation's 2017 46th Annual Symposium: Care of the Professional Voice - Keynote Speech. Dr. Joseph L. Zabner is Director of the Division of Pulmonary, Vice Chair for Translational ...Research and Professor of Internal Medicine of Pulmonary, Critical Care and Occupational Medicine at the University of Iowa Carver School of Medicine. Dr. Zabner’s research focus is on the antibacterial innate immunity in the airway epithelia, in particular how does the lack of a bicar- bonate channel ‘CFTR’ results in lung infections. Dr. Zabner’s research can be divided into 4 main areas. First, to investigate the antimicrobial properties of the airway surface liquid and how they affect bacterial colonization in cystic fibrosis.
His laboratory investigates this questions using primary cultures of human airway epithelia at the air liquid interface, animal modes including mice and pigs with deletion of the CFTR gene, and humans with cystic fibrosis. They are currently studying the effect of inhaled buffers to enhance airway innate immunity. Second, Dr. Zabner investigates the development of vectors for gene therapy in cystic fibrosis. Currently, they have been using ‘directed evolution’ to select adeno-associated viruses that efficiently target the airway epithelia of humans and pigs. The porcine model of Cystic Fibrosis will allow them to ask the question if ‘gene transfer’ can result in ‘gene therapy’ Third, his laboratory also investigates how the receptor for adenovirus regulates epithelial functions as well as pathogenesis of adenovirus airway infection. Finally, they have been investigating the effect of an endogenous lactonase ‘paraoxonase' that can degrade quorum-sensing molocules used by Pseudomonas Aeruginos. This family of proteins is ubiquitously expressed in the airways and may represent a novel form of innate immunity against quorum-sensing bacteria.
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2017 Tutorials

Tutorials take place on the first day of the Symposium to help prepare attendees for the research papers on subsequent days. They typically include Anatomy and Physiology of the Voice and Production and Perception of the Voice.

An Overview
Anatomy and Physiology of Phonation
Robert Sataloff, MD, DMA, FACS

An Overview (Larson, Sundberg)
Production and Perception of Voice I

NEURO – Charles Larson, PhD

RESPIRATION – Johan Sundberg, PhD


An Overview (Scherer, Ternström, Shrivastav, Riley)
Production and Perception of Voice II

PHONATION – Ronald S. Scherer, PhD

VOCAL TRACT – Sten Ternström, PhD,


PERCEPTION – Rahul Shrivastav, PhD



VOICE PEDAGOGY – William Riley, MM



Robert Zatorre, PhDKeynote Speech 2017, Robert Zatorre, PhD
Perception , Production and Pleasure: The Neuroscience of Music


G. Paul Moore Lecture: Sten Ternström
Mind the Gap


Quintana Research Award Lecture 2017,  Dimitar Deliyski, PhD
for engineering contributions to voice science
An Engineeer in Dysphonialand

Panels, Special Sessions

Panel: Lana Shekim, PhD, Michael M. Johns, MD
NIH Research Training and Research Career Opportunities



Friday Morning Special Session:

PART I: Transgender Voice: Insights and Updates
Nancy Pearl Solomon, Moderator

Care of the Transgender Voice: Historical Context  –  Nancy Pearl Solomon, PhD
Managing Gender Dysphoria: From Childhood to Old Age – Wylie Hembree, MD
Laryngel Surgery from Male to Female Gender Reassignment  –  Robert T. Sataloff, MD
Selecting Targets for Transgender Voice and Communication Training – Jennifer Oates, PhD

PART II: Transgender Voice: Insights and Updates

Evaluating Transgender Voice and Communication -Georgia Dacakis, MEd
Current perspectives and future directions for Transgender Voice Care – Adrienne Hancock, PhD
Panel Discussion

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